I am not familiar with it, the following is just an idea.
If next build generates a static file, you can just point the document root folder to it, so the web server can serve it.
If you want to run a nodejs + next as a back-end service, please follow https://blog.litespeedtech.com/2022.../#setting-up-openlitespeed-as-a-reverse-proxy to config OLS as a reverse proxy server.
yes, have a issue. i'm make api in node.js using typescript, but not find command for execute build or, "npm run start" script... open liteSpeed need more support for node because JavaScript this most language used today..