Well i checked in 1.4.50, 1.5.6 OLS
Those variables are not set in multiple places - however in litespeed it works!
for example
setting variable in LiteSpeed SAPI App -> Environment
PHP_INI_SCAN_DIR=/home/$VH_ROOT/$VH_DOMAIN/.php/conf.d
can lead to different php.ini included with lsphp for different vhost/domain
but it not works